Author:

Abstract

This review was constructed to evaluate the current advancements in the surgical management of colorectal cancer liver metastases. A shift from the classic conservative and palliative management of such cases has begun with transitions toward surgical management. This shift is due to multiple compounding factors of which many are being studied and presented individually. By combing these factors together, this review provides guidance on the most significant preoperative prognostic factors and suggests future treatment goals for these patients. A progressive conversion from conservative to surgical management also presents ethical implications to be considered. This review may direct future research on surgical resection of colorectal cancer liver metastases and provide advantageous information on the value of preoperative prognostic factors and the role of surgical intervention in this patient population.

Keywords: Surgical oncology, Colorectal cancer, Liver metastasis, Surgical resection, Carcinoembryonic antigen, Future liver remnant, Preoperative evaluation, Portal vein embolization, Percutaneous radiofrequency ablation, Conversion therapy, Chemotherapy, Mismatch