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    Case Report

    Neuroendocrine tumor mixed with adenoma in rectum: a case report and literature review

    Authors:

    Jiancong Hu,

    Department of Ambulatory Surgery Center, the Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, the Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, CN
    About Jiancong

    MD

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    Xiaochuan Chen,

    Department of Obstetrics and Gynecology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, CN
    About Xiaochuan

    MD

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    Dezheng Lin,

    Department of Ambulatory Surgery Center, the Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, the Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, CN
    About Dezheng

    MD

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    Zhaoliang Yu,

    Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, the Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, CN
    About Zhaoliang

    MD

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    Juan Li,

    Department of Ambulatory Surgery Center, the Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, the Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, CN
    About Juan

    MD

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    Xuefeng Guo

    Department of Ambulatory Surgery Center, the Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, the Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, CN
    About Xuefeng

    MD, PhD

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    Abstract

    Neuroendocrine tumor (NET) mixed with adenoma in rectum is rare. A 63-year-old man with a rectal adenoma underwent endoscopic submucosal dissection. A 3.2 cm neoplasm was dissected, which histologically corresponded to a villous adenoma with high-grade intraepithelial neoplasia. More interestingly, cells arranged in strip were found in the submucosa, with SyN( +) and CgA (-) in immunohistochemical staining, which were correspond to an NET. Although mixed adenoma with NET is rare, but we should alert it especially in large adenoma and full-scale preoperative evaluation should be taken before endoscopic operation.

    Keywords: Adenoma, Neuroendocrine tumor, ESD
    How to Cite: Hu J, Chen X, Lin D, Yu Z, Li J, Guo X. Neuroendocrine tumor mixed with adenoma in rectum: a case report and literature review. International Journal of Surgery: Oncology. 2019;4(6):e79. DOI: http://doi.org/10.1097/IJ9.0000000000000079
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    Published on 29 Oct 2019.
    Peer Reviewed
    CC BY 4.0

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